News : 2016

More than 600 Cancer Patients Treated at Sylvester’s Adult Stem Cell Transplant Program

Earlier this year, Sylvester Comprehensive Cancer Center, part of UHealth – the University of Miami Health System, celebrated its 500th stem cell transplant. Now, just a few months later, the cancer center announced it has conducted more than 600 stem cell transplants, making it one of the largest transplant centers of its kind in the country. Success rates are very high and the Sylvester stem cell transplant team expects to treat nearly 200 patients in the current year.

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UHealth Pediatric ENT Expert Warns of Glue Ear

Ear, nose and throat specialists, as well as pediatricians, regularly treat young patients for ear infections. Yet many of these same experts are less familiar with glue ear, known to clinicians as otitis media with effusion or secretory otitis media. Glue ear is a condition where accumulated fluid behind the ear drum becomes thick and sticky, ultimately affecting a child’s hearing.

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New Precision Therapies for Atrial Fibrillation

Though it is one of the most common heart rhythm disorders, atrial fibrillation (A-fib) can eventually lead to heart failure or stroke if not properly diagnosed and treated. Jeffrey Goldberger, M.D., M.B.A., chief of the Cardiovascular Division in the Department of Medicine at UHealth – the University of Miami Health System, is working on the development of new precision therapies that could dramatically improve the health outcomes of patients with A-fib.

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Sylvester Researcher Launches Study on Early Detection of Ovarian Cancer

Brian Slomovitz, M.D., co-leader of Sylvester Comprehensive Cancer Center’s Gynecologic Cancers Site Disease Group, is leading a new clinical study focused on the early detection of ovarian cancer in postmenopausal women. Ovarian cancer is rarely detected until it has reached an advanced stage because there are no clear early symptoms.

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What if a Pill Could be the Answer to Concussion?

The goal of finding a treatment for concussion may be one step closer due to a new study being launched by University of Miami researchers. As part of a $16 million research grant from Scythian Biosciences, researchers at the university’s The Miami Project to Cure Paralysis and Miller School of Medicine will begin studying whether a simple pill could someday be a solution to the growing concussion epidemic.

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Breathing Life, Hope, & Success into South Florida’s Thoracic Care

Thoracic case complexity – coupled with minimally invasive thoracic surgery (MITS) techniques – can equal outstanding outcomes and significantly reduce complications, especially in the hands of South Florida’s leading thoracic experts.

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Motor Improvement Seen in Patients with Cervical Spinal Cord Injury After Stem Cell Implantation

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Two National Stroke Studies Shed Light on Treatment Options for Carotid-Artery Stenosis

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UHealth Laryngologist First in South Florida to Use KTP Laser for Vocal Health

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Why the Quadriceps Graft is a Great Option for your Patient’s ACL Reconstruction

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J. William Harbour, M.D.

New Biomarker Identifies Eye Cancer Patients at High Risk for Metastasis

A study by J. William Harbour, M.D., Associate Director for Basic Research and leader of the Eye Cancer Site Disease Group at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and colleagues, published today in Clinical Cancer Research, details the discovery of a biomarker that puts patients at a higher risk for metastasis of uveal melanoma.

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Bernard S. Baumel, M.D.

UHealth Launches Clinical Trial to Treat Alzheimer’s

Neurologists at UHealth – the University of Miami Health System are starting a clinical trial to treat Alzheimer’s disease — what will be the first in the U.S. to use mesenchymal stem cells. The study, which is designed to determine the safety of this treatment strategy, will be open to patients at UHealth with mild Alzheimer’s disease symptoms who are otherwise healthy.

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From left, Alejandro Caicedo, Ph.D., Per-Olof Berggren, Ph.D., Midhat Abdulreda, Ph.D., and Rayner Rodriguez-Diaz, Ph.D.

DRI Study Shows Effects of Long-Term Drugs on Insulin-Producing Cells

An important study led by researchers at the Diabetes Research Institute (DRI) at the University of Miami’s Miller School of Medicine shows the effects of liraglutide, a popular GLP-1 analog, on the function of human pancreatic islets after long-term daily treatment in humanized mice.

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Stephen D. Nimer, M.D.

Patients Treated at Elite Group of Academic Cancer Centers Have Higher Survival Rates

A recent study by researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York, published in The Journal of the American Medical Association (JAMA), showed that patients treated at cancer centers that are part of an elite group of academic cancer research centers have a 10 percent lower chance of dying in the first year after diagnosis than those treated at community hospitals.

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Andrew V. Schally, Ph.D., M.D.h.c., D.Sc.h.c.

Miller School Researcher’s Peptide May Help Control High Levels of Lipids in Type 1 Diabetes

A peptide developed by Nobel Laureate Andrew V. Schally, Ph.D., M.D.hc (Multi), D.Sc., professor of pathology at the University of Miami Miller School of Medicine, may help control unhealthy levels of lipids in type 1 diabetes.

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Mingjiang Xu, M.D., Ph.D.

New Study Highlights Role of TET Proteins in Blood Cancers

Some proteins drive the cellular overgrowth that leads to cancer, while others act as cancer suppressors. TET1 and TET2 do both. Research led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has uncovered the role these proteins play in cancer development, potentially leading to new treatments.

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Youssef Zeidan, M.D., Ph.D.

Research Finds Botox May Reduce ‘Dry Mouth’ Following Radiation Therapy

A researcher at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has found that botulinum toxin (Botox) protects the salivary glands in mice, reducing the impact of “dry mouth” following radiation therapy.

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From left, Mehrdad Nadji, M.D., David Watkins, Ph.D., Sylvia Daunert, Pharm.D., M.S., Ph.D., Glen N. Barber, Ph.D., Sapna Deo, Ph.D., Mario Stevenson, Ph.D., and Ronald Desrosiers, Ph.D.

Miami CTSI Supports Collaborative Research Team to Study Zika Virus

As the Zika virus outbreak develops as a public health emergency, both internationally and for South Florida, David Watkins, Ph.D., professor and Vice Chair of Research in the Department of Pathology, and a team of top Miller School researchers are rapidly working to develop better diagnostic tests and to understand the virus’s link to neurological complications such as microcephaly.

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Ralph L. Sacco, M.D., M.S.

Miller School Study Findings Dispute Revised Blood Pressure Guidelines

New research finds that a recent revision in national guidelines for treating high blood pressure in people 60 and older could put this population at greater stroke risk. The increased stroke risk is even more pronounced among Hispanics and blacks, the research showed. Those are the findings of a new study in the American Heart Association’s journal Hypertension, led by Ralph L. Sacco, M.D., M.S.

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Jeffrey Goldberger, M.D., M.B.A.

Up Close with Dr. Jeffrey Goldberger: ‘We Need People to Rally Around Heart Research’

Chief of Cardiovascular Medicine Jeffrey Goldberger, M.D., M.B.A., joined UHealth – the University of Miami Health System in November. He hails from Northwestern University, where he pioneered groundbreaking heart mapping and stroke prevention tools that he’s brought to UHealth to improve the health outcomes of patients with atrial fibrillation (A-fib).

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Nick Carcioppolo, Ph.D.

New Study: Fear and Guilt Messaging Increases HPV Vaccination Intentions

In a recent joint study by Sylvester Comprehensive Cancer Center, the University of Miami School of Communication and Missouri State University, a team of scientists analyzed the impact of using a combination of guilt and fear messaging compared to a traditional fear appeal on human papillomavirus (HPV) vaccination intentions.

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Joseph Panoff, M.D.

Study Shows Inferior Outcomes for African-American Pediatric Lymphoma Patients

Researchers from Sylvester Comprehensive Cancer Center have published a study showing that African-American pediatric Hodgkin lymphoma patients have inferior overall survival to their white and Hispanic peers. The findings, published in the journal Pediatric Blood & Cancer, are the largest study yet on racial and ethnic disparity in the pediatric Hodgkin lymphoma population.

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David S. Kushner, M.D.

Rehabilitation Services Provide Significant Benefits to Patients with Brain Tumors

When neurosurgeons at Sylvester Comprehensive Cancer Center or University of Miami Hospital refer patients with a primary brain tumor to him, David S. Kushner, M.D., Medical Director for the UM rehabilitation program at HealthSouth Rehab Hospital, finds that rehabilitation can play a key role in helping them recover their functions and enjoy a higher quality of life.

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Stephen D. Nimer, M.D.

Sylvester Researchers Identify Genetic Abnormalities Driving Development of Acute Myeloid Leukemia

Researchers at Sylvester Comprehensive Cancer Center, in close collaboration with Memorial Sloan Kettering Cancer Center (MSKCC), published a study in The Journal of Experimental Medicine on January 11, mapping the interaction of various genetic abnormalities in the development of acute myeloid leukemia (AML).

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Michael Hoffer, M.D.

Researchers Identify Questions that Improve Concussion Diagnosis

A team of Miller School of Medicine researchers has published a study regarding symptom identification for mild traumatic brain injury (mTBI), also known as concussion. The research indicates that five symptom clusters — post-traumatic headache/migraine, nausea, emotion/affective, fatigue/malaise and dizziness/mild cognitive impairment — were more prevalent in those who sustained mTBI.

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From left, 200th transplant patient George Schwartz, 500th patient Keith Oliver, Miami-Dade Deputy Mayor Russell Benford, and Transplant Program Director Krishna V. Komanduri, M.D., with proclamations from the state and the county.

Sylvester Celebrates 500th Stem Cell Transplant

On January 14, more than 150 patients, their families, doctors, nurses and caretakers came to Sylvester Comprehensive Cancer Center to celebrate a tremendous milestone in the cancer center’s recent history — the 500th stem cell transplant conducted at Sylvester to treat blood disorders such as leukemia and lymphoma.

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Juan Dominguez-Bendala, Ph.D.

Diabetes Research Institute Pioneers Safer Approach for Creating Insulin-Producing Cells

Scientists at the Diabetes Research Institute at the University of Miami Miller School of Medicine have successfully converted non-insulin-producing cells of the pancreas into insulin-producing cells using a single agent, bone morphogenetic protein-7 (BMP-7), which is already approved by the Food and Drug Administration for clinical use.

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Francisco Vega, M.D., Ph.D.

Unwinding Lymphoma – How Researchers Better Understand Key Pathways

For Francisco Vega, M.D., Ph.D., Director of Hematopathology at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, sorting out cancer cell biology has been a years-long endeavor. Vega is particularly focused on the molecular signals that drive lymphoma. Several years ago, he showed that a protein called Hedgehog helps cancer cells survive in diffuse large B-cell lymphoma.

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Richard K. Lee, M.D., Ph.D., left, and Richard K. Parrish, II, M.D.

Bascom Palmer Researchers Will Study Prevalence of Glaucoma in Haitian-American Population

Researchers at the University of Miami Miller School of Medicine’s Bascom Palmer Eye Institute will be launching genetic studies in Miami’s Haitian community to identify a gene involved in controlling eye pressure that may be linked to glaucoma in all patients.

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Margaret A. Pericak-Vance, Ph.D., left, with William K. Scott, Ph.D.

International Study Reveals New Genetic Clues to Age-Related Macular Degeneration

Researchers from the University of Miami Miller School of Medicine’s John P. Hussman Institute for Human Genomics and Bascom Palmer Eye Institute are part of a consortium that has significantly expanded the number of genetic factors known to play a role in age-related macular degeneration (AMD), a leading cause of vision loss among people age 50 and older.

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